Principal/Senior Proteomics Scientist, Bioinformatics

San Mateo, CA

Who we are

At PrognomiQ, we aim to develop and commercialize transformative tests for early detection and treatment of cancer and other complex diseases. To accomplish this, we are leveraging leading proteomics technology, including the Proteograph product suite from Seer Bio, in combination with other multi-omics assays to develop unprecedented molecular views of health and disease. We are a team of experienced and accomplished scientists supported by a group of leading investors in healthcare and technology.

Would you like to be at the leading edge of molecular data generation and analyses that changes how cancer and other complex diseases are detected and treated? Or are you looking to bring innovative and disruptive solutions to market? If you answer “yes” to either of these questions, let us know by applying!

Description of role

As a key member of PrognomiQ’s bioinformatics team, you’ll be integral to the success of our mission to develop highly accurate and cost-effective diagnostic tests.


  • Critically analyze multi-omics data, particularly proteomics, metabolomics, and lipidomics to identify disease-specific signals.

  • Research and develop novel methods and approaches to address the analytical challenges inherent to analyzing proteins and metabolites in biological fluids and to capitalize on the unprecedented collection of mass spectrometry data we are generating.

  • Work closely in collaboration with laboratory and assay development scientists in order to design experiments and optimize our proteomics assays.

  • Document results of analyses and investigations in a reproducible manner and communicate insights to both experts and non-experts via presentations and publications.

  • Work effectively within an interdisciplinary environment that encompasses experts in oncology, molecular biology, assay development, and data science to further develop our platforms and products.


  • Ph.D. in bioinformatics, biostatistics, computational biology, or related discipline.

  • Expertise in mass spectrometry-based protein quantification and identification as well as the current computational tools required to process and analyze MS data.

  • Demonstrated skills in proper experimental design, troubleshooting challenges, and interpreting as well as innovating on complex mass spectrometry data.

  • Proficiency in at least one general purpose coding language such as Python or R.

  • A record of achievement as evidenced by quality publications or positions of increasing responsibility in industry.

  • Excellent communication skills and the willingness to work towards larger team goals.

Equal Opportunity Employment

PrognomiQ is an equal opportunity employer that celebrates diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other characteristic protected by law. This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, training, and apprenticeship.